概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human

相关产品

技术指标

Our Abpromise guarantee covers the use of ab39910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • Tax responsive element binding protein 5
    • Tax-responsive element-binding protein 5
    • TREB5
    • X box binding protein 1
    • X box binding protein 2
    • X-box-binding protein 1
    • XBP 1
    • XBP-1
    • XBP1
    • XBP1_HUMAN
    • XBP2
    see all
  • 功能Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
  • 疾病相关Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.
  • 序列相似性Belongs to the bZIP family.
    Contains 1 bZIP domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Human XBP1 peptide (ab39910)参考文献

ab39910 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab39910.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"