概述

  • 产品名称
    人WRCH1肽

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      PPQQGDPAFPDRCEA
    • 氨基酸
      2 to 16

技术指标

Our Abpromise guarantee covers the use of ab23007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • ARHU
    • CDC42 L1
    • CDC42 like GTPase
    • CDC42-like GTPase 1
    • CDC42L1
    • G28K
    • GTP binding protein like 1
    • GTP binding protein SB128
    • GTP-binding protein-like 1
    • hG28K
    • mG28K
    • Ras homolog gene family member U
    • Ras homolog gene family member U isoform CRA a
    • Ras like gene family member U
    • Rho GTPase like protein ARHU
    • Rho GTPase-like protein ARHU
    • Rho related GTP binding protein RhoU
    • Rho-related GTP-binding protein RhoU
    • Rhou
    • RHOU_HUMAN
    • Ryu GTPase
    • Wnt-1 responsive Cdc42 homolog 1
    • Wnt1 responsive Cdc42 homolog
    • WRCH 1
    • WRCH-1
    see all
  • 功能
    Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.
  • 组织特异性
    Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.
  • 序列相似性
    Belongs to the small GTPase superfamily. Rho family.
  • 细胞定位
    Cell membrane. Golgi apparatus membrane. Cell junction > focal adhesion. Cell projection > podosome. Localizes to podosomes in SRC-transformed cells.
  • Information by UniProt

Human WRCH1 peptide (ab23007)参考文献

ab23007 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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