概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab24282 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-UCP1 antibody (ab23841)

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Information available upon request.

常规信息

  • 别名
    • mitochondrial brown fat uncoupling protein
    • Mitochondrial brown fat uncoupling protein 1
    • SLC25A7
    • Solute carrier family 25 member 7
    • Thermogenin
    • UCP
    • UCP 1
    • UCP1
    • UCP1_HUMAN
    • Uncoupling protein 1
    • uncoupling protein 1 (mitochondrial, proton carrier)
    see all
  • 功能UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
  • 组织特异性Brown adipose tissue.
  • 序列相似性Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt

Human UCP1 peptide (ab24282)参考文献

This product has been referenced in:
  • Pearson LE  et al. To each its own: Thermoregulatory strategy varies among neonatal polar phocids. Comp Biochem Physiol A Mol Integr Physiol 178:59-67 (2014). Blocking . Read more (PubMed: 25151642) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"