概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-NKPNSGKNDDKGNK
    • 氨基酸37 to 50

相关产品

技术指标

Our Abpromise guarantee covers the use of ab45838 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-TPH2 antibody (ab40846)

  • 形式Liquid
  • 补充说明

    ab40846 Anti-TPH2 antibody is the corresponding antibody to this peptide.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

常规信息

  • 别名
    • MGC138871
    • ADHD7
    • FLJ37295
    • MGC138872
    • Neuronal tryptophan hydroxylase
    • NTPH
    • TPH 2
    • Tph2
    • TPH2_HUMAN
    • Tryptophan 5-hydroxylase 2
    • Tryptophan 5-monooxygenase 2
    • Tryptophan hydroxylase 2
    see all
  • 组织特异性Brain specific.
  • 通路Aromatic compound metabolism; serotonin biosynthesis; serotonin from L-tryptophan: step 1/2.
  • 疾病相关Genetic variation in TPH2 may influence susceptibility to major depressive disorder (MDD) [MIM:608516].
    Defects in TPH2 are the cause of susceptibility to attention deficit-hyperactivity disorder type 7 (ADHD7) [MIM:613003]. ADHD is a neurobehavioral developmental disorder and is primarily characterized by the co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone. Note=Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders.
  • 序列相似性Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    Contains 1 ACT domain.
  • Information by UniProt

Human TPH2 peptide (ab45838)参考文献

ab45838 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45838.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"