概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab39865 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • CD281
    • CD281 antigen
    • KIAA0012
    • LPRS5
    • rsc786
    • TIL
    • TIL. LPRS5
    • Tlr1
    • TLR1_HUMAN
    • Toll (Drosophila) homolog
    • Toll like receptor 1
    • Toll-like receptor 1
    • Toll/interleukin-1 receptor-like protein
    see all
  • 功能Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • 组织特异性Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
  • 序列相似性Belongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • 细胞定位Cell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt

Human TLR1 peptide (ab39865)参考文献

ab39865 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"