概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列PPTGQYTLFP LPPTLPTPVV QLHPLLPDPS APTP
    • 氨基酸299 to 332

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技术指标

Our Abpromise guarantee covers the use of ab93626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Thrombopoietin antibody (ab40664)

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • 复溶Reconstitute the peptide with a small volume of either ethanol:water (20:80 / v:v) or with acetonitrile:water (20:80 / v:v) and then dilute the stock peptide into the appropriate buffer for use.

常规信息

  • 别名
    • C mpl ligand
    • C-mpl ligand
    • Megakaryocyte colony stimulating factor
    • Megakaryocyte colony-stimulating factor
    • Megakaryocyte growth and development factor
    • Megakaryocyte stimulating factor
    • MGC163194
    • MGDF
    • MKCSF
    • ML
    • MPL ligand
    • MPLLG
    • Myeloproliferative leukemia virus oncogene ligand
    • Prepro thrombopoietin
    • THCYT1
    • THPO
    • Thrombopoietin
    • Thrombopoietin nirs variant 1
    • TPO
    • TPO_HUMAN
    see all
  • 功能Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
  • 疾病相关Defects in THPO are a cause of essential thrombocythemia (ET) [MIM:187950]. ET is inherited as an autosomal dominant trait which is characterized by elevated platelet levels due to sustained proliferation of megakaryocytes, and frequently lead to thrombotic and haemorrhagic complications.
  • 序列相似性Belongs to the EPO/TPO family.
  • 结构域Two-domain structure with an erythropoietin-like N-terminal and a Ser/Pro/Thr-rich C-terminal.
  • 细胞定位Secreted.
  • Information by UniProt

Human Thrombopoietin peptide (ab93626)参考文献

ab93626 has not yet been referenced specifically in any publications.

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