概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      CAYKWLYDETLEDR
    • 氨基酸
      383 to 396

相关产品

技术指标

Our Abpromise guarantee covers the use of ab23228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-TFB2M antibody (ab13676)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Dimethyladenosine transferase 2
    • dimethyladenosine transferase 2 mitochondrial
    • FLJ22661
    • FLJ23182
    • h mtTFB
    • h mtTFB2
    • h-mtTFB
    • h-mtTFB2
    • HCV NS5A transactivated protein 5
    • HCV NS5A-transactivated protein 5
    • hepatitis C virus NS5A transactivated protein 5
    • Hepatitis C virus NS5A-transactivated protein 5
    • Hkp1
    • hTFB2M
    • mitochondrial
    • Mitochondrial 12S rRNA dimethylase 2
    • Mitochondrial dimethyladenosine transferase 2
    • Mitochondrial transcription factor B2
    • mtTFB
    • mtTFB2
    • N''-adenosyl(rRNA) dimethyltransferase 2
    • NS5ATP5
    • S adenosylmethionine 6 N', N' adenosyl(rRNA) dimethyltransferase 2
    • S-adenosylmethionine-6-N''
    • TFB2M
    • TFB2M_HUMAN
    • Transcription Factor B2
    • Transcription factor B2 mitochondrial
    see all
  • 功能
    S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
  • 组织特异性
    Ubiquitously expressed.
  • 序列相似性
    Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
  • 细胞定位
    Mitochondrion.
  • Information by UniProt

Human TFB2M peptide (ab23228)参考文献

ab23228 has not yet been referenced specifically in any publications.

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