The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-TFB2M antibody (ab13676)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Dimethyladenosine transferase 2
dimethyladenosine transferase 2 mitochondrial
HCV NS5A transactivated protein 5
HCV NS5A-transactivated protein 5
hepatitis C virus NS5A transactivated protein 5
Hepatitis C virus NS5A-transactivated protein 5
Mitochondrial 12S rRNA dimethylase 2
Mitochondrial dimethyladenosine transferase 2
Mitochondrial transcription factor B2
N''-adenosyl(rRNA) dimethyltransferase 2
S adenosylmethionine 6 N', N' adenosyl(rRNA) dimethyltransferase 2
Transcription Factor B2
Transcription factor B2 mitochondrial
功能S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
序列相似性Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.