TRAF family member associated NF KAPPA B activator
TRAF family member associated NFKB activator
TRAF family member-associated NF-kappa-B activator
TRAF interacting protein
TRAF interacting protein TANK isoform a
TRAF interacting protein TANK isoform b
功能Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.