概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab16634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-SPHK1 antibody (ab16491)

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Information available upon request.

常规信息

  • 别名
    • SK 1
    • SK1
    • Sphingosine kinase 1
    • SPHK
    • SPHK 1
    • Sphk1
    • SPHK1_HUMAN
    • SPK
    • SPK 1
    see all
  • 功能Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
  • 组织特异性Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.
  • 序列相似性Contains 1 DAGKc domain.
  • Information by UniProt

Human SPHK1 peptide 图像

  • ab16491 detects the tagged recombinant SPHK1 at the correct predicted molecular weight of 69kDa. This band is successfully blocked by the addition of the immunizing peptide (ab16634).

Human SPHK1 peptide (ab16634)参考文献

ab16634 has not yet been referenced specifically in any publications.

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Wegot the data over the IHC-P from a cooperator from us, and haven't validated the sensitivity our self. However, we do have the blocking peptide available if you want to use this to validate this for your experi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"