概述

  • 产品名称人SORBS1肽

描述

  • 性质Synthetic
  • 来源CHO cells
  • 氨基酸序列
    • 种属Human
    • 序列C-GTFPGNYVKPLYL

相关产品

技术指标

Our Abpromise guarantee covers the use of ab18388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-SORBS1 antibody (ab4551)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • c-Cbl-associated protein
    • CAP
    • CBL Associated Protein
    • Ponsin
    • SH3 domain protein 5
    • SH3D5
    • SH3P12
    • Sorbin and SH3 Domain Containing 1
    • Sorbin and SH3 domain-containing protein 1
    • Sorbs1
    • SRBS1_HUMAN
    see all
  • 功能Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
  • 组织特异性Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.
  • 序列相似性Contains 3 SH3 domains.
    Contains 1 SoHo domain.
  • 翻译后修饰O-glycosylated.
  • 细胞定位Cell junction > adherens junction. Cell membrane. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalized with PXN at focal adhesions during myogenic differentiation.
  • Information by UniProt

Human SORBS1 peptide (ab18388)参考文献

ab18388 has not yet been referenced specifically in any publications.

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