概述

  • 产品名称人SNX18肽

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-KVQRVPLMTVLSF
    • 氨基酸616 to 628

相关产品

技术指标

Our Abpromise guarantee covers the use of ab22972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-SNX18 antibody (ab3941)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • FLJ11997
    • FLJ32560
    • FLJ61062
    • MGC150827
    • MGC150829
    • SH3 and PX domain containing protein 3B
    • SH3 and PX domain-containing protein 3B
    • SH3PX2
    • SH3PXD3B
    • SNAG 1
    • SNAG1
    • SNX18
    • SNX18_HUMAN
    • Sorting nexin 18
    • Sorting nexin associated golgi protein 1
    • Sorting nexin-18
    • Sorting nexin-associated Golgi protein 1
    see all
  • 功能May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
  • 序列相似性Belongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • 结构域The PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate.
  • 细胞定位Endomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.
  • Information by UniProt

Human SNX18 peptide (ab22972)参考文献

ab22972 has not yet been referenced specifically in any publications.

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