概述

  • 产品名称
    人SNX18肽

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      C-KVQRVPLMTVLSF
    • 氨基酸
      616 to 628

相关产品

技术指标

Our Abpromise guarantee covers the use of ab22972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-SNX18 antibody (ab3941)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • FLJ11997
    • FLJ32560
    • FLJ61062
    • MGC150827
    • MGC150829
    • SH3 and PX domain containing protein 3B
    • SH3 and PX domain-containing protein 3B
    • SH3PX2
    • SH3PXD3B
    • SNAG 1
    • SNAG1
    • SNX18
    • SNX18_HUMAN
    • Sorting nexin 18
    • Sorting nexin associated golgi protein 1
    • Sorting nexin-18
    • Sorting nexin-associated Golgi protein 1
    see all
  • 功能
    May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
  • 序列相似性
    Belongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • 结构域
    The PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate.
  • 细胞定位
    Endomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.
  • Information by UniProt

Human SNX18 peptide (ab22972)参考文献

ab22972 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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