人SIAH Interacting Protein肽(ab23014)

概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-VESREKQAKGDTEF
    • 氨基酸215 to 228

技术指标

Our Abpromise guarantee covers the use of ab23014 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • CacyBP
    • Calcyclin binding protein
    • Calcyclin-binding protein
    • CYBP_HUMAN
    • GIG 5
    • GIG5
    • Growth inhibiting gene 5
    • Growth inhibiting gene 5 protein
    • hCacyBP
    • MGC87971
    • PNAS 107
    • PNAS107
    • RP1 102G20.6
    • S100A6 binding protein
    • S100A6-binding protein
    • S100A6BP
    • Siah-interacting protein
    • SIP
    see all
  • 功能May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
  • 序列相似性Contains 1 CS domain.
    Contains 1 SGS domain.
  • 翻译后修饰Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations.
  • 细胞定位Nucleus. Cytoplasm. Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated.
  • Information by UniProt

Human SIAH Interacting Protein peptide (ab23014)参考文献

ab23014 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23014.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"