抗人Serum Albumin抗体(ab19180)
Key features and details
- Goat polyclonal to Human Serum Albumin
- Suitable for: ICC, ELISA, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
抗人Serum Albumin抗体
参阅全部 Human Serum Albumin 一抗 -
描述
山羊多克隆抗体to人Serum Albumin -
宿主
Goat -
经测试应用
适用于: ICC, ELISA, WBmore details -
种属反应性
与反应: Human -
免疫原
Full length protein corresponding to Human Human Serum Albumin. Serum albumin
Database link: P02768 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 6.8
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab19180于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC |
Use at an assay dependent concentration.
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ELISA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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说明 |
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ICC
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
组织特异性
Plasma. -
疾病相关
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
序列相似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
翻译后修饰
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
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别名
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab19180 被引用在 5 文献中.
- Nakashima F et al. Structural and functional insights into S-thiolation of human serum albumins. Sci Rep 8:932 (2018). PubMed: 29343798
- Nehring J et al. Autoantibodies Against Albumin in Patients With Systemic Lupus Erythematosus. Front Immunol 9:2090 (2018). PubMed: 30333817
- Zheng Z et al. Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model. PLoS One 12:e0184127 (2017). PubMed: 28886065
- Brandstätter H et al. Purification and biochemical characterization of functional complement factor H from human plasma fractions. Vox Sang 103:201-12 (2012). PubMed: 22497541
- Ding YD et al. A sandwich ELISA for assessment of pharmacokinetics of HSA-(BNP)2 fusion protein in mouse plasma. J Pharm Biomed Anal 51:658-63 (2010). ELISA . PubMed: 19836183