概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      KRFLEDTTDDGE amino acids 3 to 14 of human ARTS (1).
    • 氨基酸
      3 to 14

相关产品

技术指标

Our Abpromise guarantee covers the use of ab9652 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-SEPT4 antibody (ab9651)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

常规信息

  • 别名
    • Apoptosis-related protein in the TGF-beta signaling pathway
    • ARTS
    • Bradeion
    • Bradeion beta
    • Brain protein H5
    • CE5B3
    • CE5B3 beta
    • Cell division control-related protein 2
    • Cerebral protein 7
    • H5
    • hCDCREL-2
    • hucep-7
    • MART
    • Peanut-like protein 2
    • PNUTL2
    • SEP 4
    • SEP4
    • Sept4
    • SEPT4_HUMAN
    • Septin M
    • Septin-4
    see all
  • 功能
    Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
  • 组织特异性
    Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in platelets.
  • 序列相似性
    Belongs to the septin family.
  • 细胞定位
    Cytoplasm. Cytoplasm > cytoskeleton. In platelets, found in areas surrounding alpha-granules and Mitochondrion. Nucleus. While predominantly localized in the mitochondria under resting conditions, isoform ARTS translocates into the nucleus after TGF-beta treatment and apoptosis induction.
  • Information by UniProt

文献

ab9652 has not yet been referenced specifically in any publications.

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