概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列MSNADFAKLFLRK
    • 氨基酸951 to 963

相关产品

技术指标

Our Abpromise guarantee covers the use of ab45492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-SART3 antibody (ab36137)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

常规信息

  • 别名
    • DSAP1
    • hSART 3
    • hSART-3
    • P100
    • P110
    • p110(nrb)
    • RP11 13G14
    • SART 3
    • SART-3
    • SART3
    • SART3_HUMAN
    • Squamous cell carcinoma antigen recognized by T cells 3
    • Squamous cell carcinoma antigen recognized by T-cells 3
    • Tat interacting protein of 110 kDa
    • Tat-interacting protein of 110 kDa
    • Tip110
    see all
  • 功能Regulates Tat transactivation activity through direct interaction. May be a cellular factor for HIV-1 gene expression and viral replication.
  • 组织特异性Ubiquitously expressed.
  • 疾病相关Defects in SART3 are the cause of disseminated superficial actinic porokeratosis type 1 (DSAP1) [MIM:175900]. DSAP1 is an autosomal dominant disorder, characterized by multiple superficial keratotic lesions surrounded by a slightly raised keratotic border, developing during the third or fourth decade of life on sun-exposed areas of skin.
  • 序列相似性Contains 8 HAT repeats.
    Contains 2 RRM (RNA recognition motif) domains.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm. Nucleus speckle. Localized in speckles. Expressed in the nucleus of all of the malignant tumor cell lines tested and the majority of cancer tissues with various histologies, including squamous cell carcinomas (SCC), adenocarcinomas, melanomas and leukemias cells. However, this protein is undetectable in the nucleus of any cell lines of nonmalignant cells or normal tissues, except for the testis. Expressed in the cytoplasm of all the proliferating cells, including normal and malignant cells, but not in normal tissues, except for the testis and the fetal liver.
  • Information by UniProt

Human SART3 peptide (ab45492)参考文献

ab45492 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45492.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"