The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-SAP130 antibody (ab3608)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
130 kDa Sin3-associated polypeptide
Histone deacetylase complex subunit SAP130
mSin3A associated protein 130
Pre mRNA splicing factor SF3b 130 kDa subunit
Sin3-associated polypeptide p130
Sin3A associated protein
Sin3A associated protein 130kDa
Spliceosome associated protein 130
Splicing factor 3b subunit 3
Splicing factor 3b subunit 3 130kDa
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Expressed in various cancer cell ines.
Belongs to the SAP130 family.
The N-terminus may interact with a transcriptional coactivator. The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.