概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      AAQGEPQVQFKLV-C
    • 氨基酸
      2 to 14

相关产品

技术指标

Our Abpromise guarantee covers the use of ab23304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Ran antibody (ab17033)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Androgen receptor associated protein 24
    • Androgen receptor-associated protein 24
    • ARA 24
    • ARA24
    • Gsp1
    • GTP binding nuclear protein RAN
    • GTP-binding nuclear protein Ran
    • GTPase Ran
    • Guanosine triphosphatase Ran
    • LPS
    • OK/SW-cl.81
    • ran
    • RAN member RAS oncogene family
    • RAN_HUMAN
    • RanGTPase
    • Ras like protein TC4
    • Ras related nuclear protein
    • Ras-like protein TC4
    • Ras-related nuclear protein
    • RASL2 8
    • TC 4
    • TC4
    see all
  • 功能
    GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
    Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
  • 组织特异性
    Expressed in a variety of tissues.
  • 序列相似性
    Belongs to the small GTPase superfamily. Ran family.
  • 翻译后修饰
    The N-terminus is blocked.
  • 细胞定位
    Nucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

文献

ab23304 has not yet been referenced specifically in any publications.

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