概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列CAGDRLTGIPSHILNSSPSD Amino acids 99 to 117 of human RAIDD (1,2)
    • 氨基酸99 to 117

技术指标

Our Abpromise guarantee covers the use of ab8460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-RAIDD antibody (ab8426)

    Western blot

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

常规信息

  • 别名
    • CASP2 and RIPK1 domain containing adaptor with death domain
    • Caspase and RIP adapter with death domain
    • Caspase and RIP adaptor with death domain
    • Cradd
    • CRADD_HUMAN
    • Death adaptor molecule RAIDD
    • Death domain containing protein CRADD
    • Death domain-containing protein CRADD
    • MGC9163
    • RIP associated ICH1/CED3 homologous protein with death domain
    • RIP associated protein with a death domain
    • RIP-associated protein with a death domain
    see all
  • 功能Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
  • 组织特异性Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
  • 序列相似性Contains 1 CARD domain.
    Contains 1 death domain.
  • 结构域Contains a death domain involved in the binding of RIP protein.
    The CARD domain mediates the interaction with caspase-2.
  • Information by UniProt

Human RAIDD peptide (ab8460)参考文献

ab8460 has not yet been referenced specifically in any publications.

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