概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列PQPTRQQKRACSLL
    • 氨基酸179 to 192

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技术指标

Our Abpromise guarantee covers the use of ab22892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-RAC2 antibody (ab2244)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • EN 7
    • EN-7
    • EN7
    • GX
    • HSPC 022
    • HSPC022
    • p21 Rac 2
    • p21 Rac2
    • p21-Rac2
    • p21Rac2
    • RAC 2
    • Rac2
    • RAC2_HUMAN
    • Ras related C3 botulinum toxin substrate 2
    • Ras related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2
    • Ras related C3 botulinum toxin substrate 3
    • Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac2)
    • Ras-related C3 botulinum toxin substrate 2
    • Rho family small GTP binding protein Rac 2
    • Rho family small GTP binding protein Rac2
    • Small G protein
    see all
  • 功能Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
  • 组织特异性Hematopoietic specific.
  • 疾病相关Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome (NEUID) [MIM:608203].
  • 序列相似性Belongs to the small GTPase superfamily. Rho family.
  • 细胞定位Cytoplasm. Membrane-associated when activated.
  • Information by UniProt

Human RAC2 peptide (ab22892)参考文献

ab22892 has not yet been referenced specifically in any publications.

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