The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Rabenosyn 5 antibody (ab21196)
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Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
110 kDa protein
FYVE finger containing Rab5 effector protein Rabenosyn 5
FYVE finger-containing Rab5 effector protein rabenosyn-5
zinc finger FYVE domain containing 20
Zinc finger FYVE domain-containing protein 20
功能Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).