概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      NRPAPVEVSYKHMR-C
    • 氨基酸
      5 to 18

技术指标

Our Abpromise guarantee covers the use of ab22906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Potentially prenylated protein tyrosine phosphatase
    • PRL 3
    • PRL R
    • PRL-3
    • PRL-R
    • PRL3
    • PRLR
    • Protein tyrosine phosphatase 4a3
    • Protein tyrosine phosphatase type IVA 3
    • Protein-tyrosine phosphatase 4a3
    • Protein-tyrosine phosphatase of regenerating liver 3
    • PTP 4A3
    • PTP4A3
    • TP4A3_HUMAN
    see all
  • 功能
    Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
  • 组织特异性
    Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis.
  • 序列相似性
    Belongs to the protein-tyrosine phosphatase family.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻译后修饰
    Farnesylated. Farnesylation is required for membrane targeting.
  • 细胞定位
    Cell membrane. Early endosome.
  • Information by UniProt

Human PTP4A3 peptide (ab22906)参考文献

ab22906 has not yet been referenced specifically in any publications.

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