The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-PTBP1 antibody (ab5642)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
57 kDa RNA binding protein PPTB 1
57 kDa RNA-binding protein PPTB-1
Heterogeneous nuclear ribonucleoprotein I
Heterogeneous Nuclear Ribonucleoprotein Polypeptide I
Polypyrimidine tract binding protein
Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I)
Polypyrimidine Tract Binding Protein 1
Polypyrimidine tract-binding protein 1
RNA Binding Protein
功能Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.