概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab68691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • FAAR
    • MGC3931
    • NR1C2
    • NUC1
    • NUCI
    • NUCII
    • Nuclear hormone receptor 1
    • Nuclear receptor subfamily 1 group C member 2
    • Peroxisome proliferative activated receptor delta
    • Peroxisome proliferator-activated receptor beta
    • Peroxisome proliferator-activated receptor beta (PPAR-beta)
    • Peroxisome proliferator-activated receptor delta
    • PPAR beta
    • PPAR-beta
    • PPAR-delta
    • PPAR-ß
    • PPARB
    • ppard
    • PPARD_HUMAN
    see all
  • 功能Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
  • 组织特异性Ubiquitous with maximal levels in placenta and skeletal muscle.
  • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Human PPAR delta peptide (ab68691)参考文献

ab68691 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"