概述

  • 产品名称人Pokemon肽

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-GAATDGNFTAGLA
    • 氨基酸572 to 584

技术指标

Our Abpromise guarantee covers the use of ab23084 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Factor binding IST protein 1
    • Factor that binds to inducer of short transcripts protein 1
    • FBI 1
    • FBI-1
    • FBI1
    • HIV 1 1st binding protein 1
    • HIV-1 1st-binding protein 1
    • Leukemia/lymphoma related factor
    • Leukemia/lymphoma-related factor
    • LRF
    • POK erythroid myeloid ontogenic factor
    • Pokemon
    • POZ and Krueppel erythroid myeloid ontogenic factor
    • TIP21
    • TTF I interacting peptide 21
    • TTF-I-interacting peptide 21
    • ZBT7A_HUMAN
    • ZBTB7
    • ZBTB7A
    • Zinc finger and BTB domain containing protein 7A
    • Zinc finger and BTB domain-containing protein 7A
    • Zinc finger protein 857A
    see all
  • 功能Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
  • 组织特异性Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
  • 序列相似性Contains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • 细胞定位Nucleus.
  • Information by UniProt

Human Pokemon peptide (ab23084)参考文献

ab23084 has not yet been referenced specifically in any publications.

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