The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Factor binding IST protein 1
Factor that binds to inducer of short transcripts protein 1
HIV 1 1st binding protein 1
HIV-1 1st-binding protein 1
Leukemia/lymphoma related factor
POK erythroid myeloid ontogenic factor
POZ and Krueppel erythroid myeloid ontogenic factor
TTF I interacting peptide 21
TTF-I-interacting peptide 21
Zinc finger and BTB domain containing protein 7A
Zinc finger and BTB domain-containing protein 7A
Zinc finger protein 857A
功能Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
组织特异性Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).