概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列This sequence is highly conserved in rat and mouse paxillin and is found in all three isoforms, alpha, beta and gamma.

技术指标

Our Abpromise guarantee covers the use of ab42723 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

    ELISA

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: PBS

常规信息

  • 别名
    • FLJ16691
    • FLJ23042
    • Paired box protein Pax 1
    • PAX 1
    • PAX1
    • PAXI_HUMAN
    • Paxillin
    • Paxillin alpha
    • PXN
    • PXN protein
    see all
  • 功能Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
  • 序列相似性Belongs to the paxillin family.
    Contains 4 LIM zinc-binding domains.
  • 翻译后修饰Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
  • 细胞定位Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
  • Information by UniProt

Human Paxillin peptide (ab42723)参考文献

ab42723 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"