概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human

相关产品

技术指标

Our Abpromise guarantee covers the use of ab51490 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Nicastrin antibody (ab45425)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • Anterior pharynx defective 2
    • APH 2
    • APH2
    • ATAG1874
    • KIAA0253
    • Ncstn
    • NCT
    • NICA_HUMAN
    • Nicastrin
    • RP11 517F10.1
    • RP11517F101
    see all
  • 功能
    Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
  • 组织特异性
    Widely expressed.
  • 序列相似性
    Belongs to the nicastrin family.
  • 细胞定位
    Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Human Nicastrin peptide (ab51490)参考文献

ab51490 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab51490.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册