概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-RLIATQPISASDSG
    • 氨基酸449 to 462

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技术指标

Our Abpromise guarantee covers the use of ab22793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-NFIL3 antibody (ab1078)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • E4 promoter binding protein 4
    • E4 promoter-binding protein 4
    • E4BP 4
    • E4BP4
    • E4BP4 protein
    • IL3BP 1
    • IL3BP1
    • Interleukin 3 binding protein 1
    • Interleukin 3 promoter transcriptional activator
    • Interleukin-3 promoter transcriptional activator
    • Interleukin-3-binding protein 1
    • NFIL 3
    • NFIL 3A
    • NFIL3
    • NFIL3_HUMAN
    • NFIL3A
    • Nuclear factor interleukin 3 regulated
    • Nuclear factor interleukin-3-regulated protein
    • Transcriptional activator NF IL3A
    • Transcriptional activator NF-IL3A
    see all
  • 功能Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death.
  • 组织特异性Expressed in bladder stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and muscle.
  • 序列相似性Belongs to the bZIP family. NFIL3 subfamily.
    Contains 1 bZIP domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Human NFIL3 peptide (ab22793)参考文献

ab22793 has not yet been referenced specifically in any publications.

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