概述

  • 产品名称
    人Neuro D4肽

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      C-HLKEKASAYITLT
    • 氨基酸
      341 to 353

相关产品

技术指标

Our Abpromise guarantee covers the use of ab22971 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Neuro D4 antibody (ab3940)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • BAF45B
    • BRG1-associated factor 45B
    • D4
    • D4 zinc and double PHD fingers family 1
    • DPF1
    • DPF1_HUMAN
    • NEUD4
    • Neuro d4 homolog
    • Zinc and double PHD fingers family 1
    • Zinc finger protein neuro-d4
    see all
  • 功能
    May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
  • 序列相似性
    Belongs to the requiem/DPF family.
    Contains 2 PHD-type zinc fingers.
  • 细胞定位
    Cytoplasm. Nucleus.
  • Information by UniProt

文献

ab22971 has not yet been referenced specifically in any publications.

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