人Nestin肽(ab19375)

概述

  • 产品名称人Nestin肽

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab19375 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Nestin antibody - Neural Stem Cell Marker (ab92391)

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • ESTM 46
    • FLJ 21841
    • FLJ21841
    • Intermediate filament protein
    • Nbla00170
    • nes
    • NEST_HUMAN
    • Nestin
    see all
  • 功能Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
  • 组织特异性CNS stem cells.
  • 序列相似性Belongs to the intermediate filament family.
  • 发展阶段Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments.
  • 翻译后修饰Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
  • Information by UniProt

Human Nestin peptide (ab19375)参考文献

ab19375 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

The product ab19375 is a 18 amino acid long peptide that can be used to block the antibody ab92391. We have never used this peptide in functional studies e.g. in-vitro or in-vivo. I am sorry we are unable to conf...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"