概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human

相关产品

技术指标

Our Abpromise guarantee covers the use of ab39793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    Blocking - Blocking peptide for Anti-NADE antibody (ab21303)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • Bex
    • BEX3
    • BEX3_HUMAN
    • Brain expressed X linked 3 (mouse) homolog
    • brain expressed, X-linked 3
    • Brain-expressed X-linked gene 3
    • Brain-expressed X-linked protein 3
    • DXS6984E
    • HGR74
    • Nerve growth factor receptor (TNFRSF16) associated protein 1
    • Nerve growth factor receptor associated protein 1
    • Nerve growth factor receptor-associated protein 1
    • NGFR-associated protein 1
    • NGFRAP1
    • Ovarian granulosa cell 13.0 kDa protein HGR74
    • Ovarian granulosa cell protein
    • ovarian granulosa cell protein (13kD)
    • p75NTR associated cell death executor
    • p75NTR-associated cell death executor
    • Protein BEX3
    see all
  • 功能
    May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
  • 组织特异性
    Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
  • 序列相似性
    Belongs to the BEX family.
  • 结构域
    The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.
  • 翻译后修饰
    Ubiquitinated. Degraded by the proteasome.
  • 细胞定位
    Nucleus. Cytoplasm. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.
  • Information by UniProt

文献

ab39793 has not yet been referenced specifically in any publications.

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