Nerve growth factor receptor (TNFRSF16) associated protein 1
Nerve growth factor receptor associated protein 1
Nerve growth factor receptor-associated protein 1
NGFR-associated protein 1
Ovarian granulosa cell 13.0 kDa protein HGR74
Ovarian granulosa cell protein
ovarian granulosa cell protein (13kD)
p75NTR associated cell death executor
p75NTR-associated cell death executor
功能May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
组织特异性Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
序列相似性Belongs to the BEX family.
结构域The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.
翻译后修饰Ubiquitinated. Degraded by the proteasome.
细胞定位Nucleus. Cytoplasm. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.