概述

  • 产品名称人Myosin 18B肽

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-DDVASIMKKYLQK
    • 氨基酸2555 to 2567

技术指标

Our Abpromise guarantee covers the use of ab45499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • BK125H2.1
    • DKFZp434C2422
    • DKFZp779C1668
    • MY18B_HUMAN
    • MYO18B
    • myosin 18B
    • myosin XVIIIB
    • Myosin-XVIIIb
    see all
  • 功能May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth.
  • 组织特异性Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
  • 序列相似性Contains 1 IQ domain.
    Contains 1 myosin head-like domain.
  • 发展阶段Reaches an expression peak in the third day after induction and remains at similar level during successive myotubule maturation.
  • 细胞定位Cytoplasm. Nucleus. Cytoplasm > myofibril > sarcomere. Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
  • Information by UniProt

Human Myosin 18B peptide (ab45499)参考文献

ab45499 has not yet been referenced specifically in any publications.

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