The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Moesin antibody (ab50430)
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Epididymis luminal protein 70
Membrane organizing extension spike protein
Membrane-organizing extension spike protein
Moesin/anaplastic lymphoma kinase fusion protein
功能Probably involved in connections of major cytoskeletal structures to the plasma membrane.
组织特异性In all tissues and cultured cells studied.
序列相似性Contains 1 FERM domain.
翻译后修饰Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures.
细胞定位Cell membrane. Cytoplasm > cytoskeleton. Apical cell membrane. Cell projection > microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment.