人Mannan Binding Lectin肽(237-248) (Carboxyterminal end) (ab45655)

概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      STSHLAVCEFPI
    • 氨基酸
      237 to 248

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技术指标

Our Abpromise guarantee covers the use of ab45655 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Mannan Binding Lectin antibody (ab31296)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

常规信息

  • 别名
    • COLEC 1
    • COLEC1
    • Collectin-1
    • HSMBPC
    • Lectin, mannose-binding, soluble, 2
    • Mannan binding lectin
    • Mannan binding protein
    • Mannan-binding protein
    • Mannose binding lectin
    • Mannose binding lectin (protein C) 2 soluble
    • Mannose binding lectin (protein C) 2, soluble
    • Mannose binding lectin (protein C) 2, soluble (opsonic defect)
    • Mannose binding lectin 2 soluble
    • Mannose binding lectin 2, soluble (opsonic defect)
    • Mannose binding lectin protein C2 soluble opsonic defect
    • Mannose binding protein
    • Mannose binding protein C
    • Mannose binding protein C precursor
    • Mannose binding protein, serum
    • Mannose-binding lectin
    • Mannose-binding protein C
    • MBL
    • MBL 2
    • MBL2
    • MBL2_HUMAN
    • MBL2D
    • MBP
    • MBP 1
    • MBP C
    • MBP-C
    • MBP1
    • MBPB
    • MBPC
    • MBPD
    • MGC116832
    • MGC116833
    • Opsonic defect
    • protein C
    • Soluble mannose binding lectin
    see all
  • 功能
    Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
  • 组织特异性
    Plasma protein produced mainly in the liver.
  • 疾病相关
    Note=There is an association between low levels of MBL2 and a defect of opsonization which results in susceptibility to frequent and chronic infections.
  • 序列相似性
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • 细胞定位
    Secreted.
  • Information by UniProt

Human Mannan Binding Lectin peptide (237-248) (Carboxyterminal end) (ab45655)参考文献

ab45655 has not yet been referenced specifically in any publications.

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