概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab74029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Kindlin 2 antibody (ab74030)

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • FLJ34213
    • FLJ44462
    • UNC112
    • FERM2_HUMAN
    • Fermitin family homolog 2
    • Fermt2
    • KIND2
    • Kindlin-2
    • MIG-2
    • MIG2
    • Mitogen-inducible gene 2 protein
    • PH domain-containing family C member 1
    • Pleckstrin homology domain containing family C (with FERM domain) member 1
    • Pleckstrin homology domain-containing family C member 1
    • PLEKHC1
    • UNC112B
    see all
  • 功能Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.
  • 组织特异性Ubiquitous. Found in numerous tumor tissues.
  • 序列相似性Belongs to the kindlin family.
    Contains 1 FERM domain.
    Contains 1 PH domain.
  • 结构域The FERM domain is not correctly detected by PROSITE or Pfam techniques because it contains the insertion of a PH domain.
  • 细胞定位Cytoplasm > cell cortex. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Within actin stress fibers at cell-ECM focal adhesion sites.
  • Information by UniProt

Human Kindlin 2 peptide (ab74029)参考文献

ab74029 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"