概述

描述

  • 性质Synthetic

技术指标

Our Abpromise guarantee covers the use of ab21996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Islet 1 antibody - Neural Stem Cell Marker (ab20670)

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Insulin gene enhancer protein ISL 1
    • Insulin gene enhancer protein ISL-1
    • Insulin related protein
    • ISL 1
    • ISL LIM homeobox 1
    • ISL1
    • ISL1 transcription factor LIM homeodomain
    • ISL1 transcription factor, LIM/homeodomain
    • ISL1 transcription factor, LIM/homeodomain (islet 1)
    • ISL1_HUMAN
    • Islet-1
    • Islet1
    see all
  • 功能Binds to one of the cis-acting domain of the insulin gene enhancer.
  • 组织特异性Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
  • 序列相似性Contains 1 homeobox DNA-binding domain.
    Contains 2 LIM zinc-binding domains.
  • 细胞定位Nucleus.
  • Information by UniProt

Human Islet 1 peptide (ab21996)参考文献

This product has been referenced in:
  • Moreno N  et al. Characterization of the bed nucleus of the stria terminalis in the forebrain of anuran amphibians. J Comp Neurol 520:330-63 (2012). Read more (PubMed: 21674496) »
  • Moreno N  et al. Islet1 as a marker of subdivisions and cell types in the developing forebrain of Xenopus. Neuroscience 154:1423-39 (2008). Read more (PubMed: 18515014) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"