Anti-Human IgM抗体[R1/69] (ab17104)

概述

  • 产品名称Anti-Human IgM抗体[R1/69]
    参阅全部 Human IgM 一抗
  • 描述
    小鼠单克隆抗体[R1/69] to人IgM
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human lymphoid cells.

  • 阳性对照
    • Tonsil
  • 常规说明


    This antibody reacts with the heavy chain present in all types of human IgM.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, Tissue culture supernatant
  • 纯度Tissue culture supernatant
  • Primary antibody说明This antibody reacts with the heavy chain present in all types of human IgM.
  • 克隆单克隆
  • 克隆编号R1/69
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab17104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/25 - 1/50. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.

1/25 - 1/50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature.

靶标

  • 相关性IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. IgM measurement yields information about the body's immediate resistance and response to infection as well as information related to specific diseases. Decreased levels are associated with immune deficiency states, hereditary deficiencies, and myeloma. Increased levels can be associated with Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease.
  • 细胞定位Cell Membrane and Secreted
  • 数据库链接
  • 别名
    • Immunoglobin heavy chain constant region mu edit item name - Immunoglobin heavy chain mu constant region antibody
    • Immunoglobin heavy chain constant region mu antibody
    • AGM1 antibody
    • Constant region of heavy chain of IgM antibody
    • DKFZp686I15196 antibody
    • DKFZp686I15212 antibody
    • FLJ00385 antibody
    • Ig mu chain C region antibody
    • IGHM antibody
    • IgM heavy chain constant region antibody
    • Immunoglobin heavy constant mu antibody
    • Immunoglobulin mu antibody
    • MGC104996 antibody
    • MGC52291 antibody
    • MU antibody
    • VH antibody
    see all

Anti-Human IgM antibody [R1/69] 图像

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded human spleen tissue sections, labelling IgM with ab17104.

Anti-Human IgM antibody [R1/69] (ab17104)参考文献

ab17104 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab17104.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"