Anti-Human IgG抗体- ChIP Grade (ab2410)

概述

  • 产品名称Anti-Human IgG抗体- ChIP Grade
    参阅全部 Human IgG 一抗
  • 描述
    兔多克隆抗体to人IgG - ChIP Grade
  • 经测试应用适用于: ChIP, Flow Cyt, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    IgG isolated from a pool of normal human sera.

  • 阳性对照
    • Tonsil

性能

应用

Our Abpromise guarantee covers the use of ab2410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ChIP Use at an assay dependent dilution. PubMed: 15252039Used as negative isotype control in PMID 15252039.
Flow Cyt Use at an assay dependent dilution.
IHC-P 1/200 - 1/500. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
IHC-Fr Use at an assay dependent dilution.

靶标

  • 相关性IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • FLJ39988 antibody
    • FLJ40036 antibody
    • FLJ40253 antibody
    • FLJ40587 antibody
    • FLJ40789 antibody
    • FLJ40834 antibody
    • G1m marker antibody
    • G2m marker antibody
    • G3m marker antibody
    • G4m marker antibody
    • HDC antibody
    • Heavy chain disease protein antibody
    • Human immunglobulin G antibody
    • Ig gamma 1 chain C region antibody
    • Ig gamma 2 chain C region antibody
    • Ig gamma 3 chain C region antibody
    • Ig gamma 4 chain C region antibody
    • IgG heavy chain locus antibody
    • IGHG 1 antibody
    • IGHG 2 antibody
    • IGHG 3 antibody
    • IGHG 4 antibody
    • IGHG1 antibody
    • IGHG2 antibody
    • IGHG3 antibody
    • IGHG4 antibody
    • Immunoglobulin Gm1 antibody
    • Immunoglobulin Gm3 antibody
    • Immunoglobulin Gm4 antibody
    • immunoglobulin heavy constant gamma 1 (G1m marker) antibody
    • Immunoglobulin heavy constant gamma 1 antibody
    • immunoglobulin heavy constant gamma 2 (G2m marker) antibody
    • Immunoglobulin heavy constant gamma 2 antibody
    • immunoglobulin heavy constant gamma 3 (G3m marker) antibody
    • Immunoglobulin heavy constant gamma 3 antibody
    • immunoglobulin heavy constant gamma 4 (G4m marker) antibody
    • Immunoglobulin heavy constant gamma 4 antibody
    • MGC117419 antibody
    • MGC45809 antibody
    see all

Anti-Human IgG antibody - ChIP Grade 图像

  • ab2410 staining IgG in human tonsil sections

Anti-Human IgG antibody - ChIP Grade (ab2410)参考文献

This product has been referenced in:
  • Kasembeli M  et al. Modulation of STAT3 folding and function by TRiC/CCT chaperonin. PLoS Biol 12:e1001844 (2014). IP ; Human . Read more (PubMed: 24756126) »
  • Chen MC  et al. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1a/VEGF signaling pathway in human bladder cancer cells. Biochem Pharmacol 85:1278-87 (2013). Read more (PubMed: 23416116) »

See all 7 Publications for this product

Product Wall

We have not received any report of the this antibody being used for diagnosis of autoimmune diseases by IHC or other methods. It has been demonstrated to be capable of staining a sub-population of cells in tonsil sections, as shown on the datasheet, bu...

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Thank you for your call today and for your questions.

Here are the products that we discussed:

1) Rabbit anti-human IgG (H&L) antibody: Ab6715

http://www.abcam.com/Rabbit-polyclonal-Secondary-Antibody-to-Human-IgG-H-L-...

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Thank you for your reply.

I attached the MSDS to this email for your information.

I hope this ids helpful and wish you good luck with your research.

Thank you for your inquiry.

The MSDS PDFsfor our products can be found on the online datasheets.

If there is not MSDS as in the case of ab2410, this indicates that the product does not contains hazardous substances or only contains ...

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Vielen Dank für Ihre Nachrichten.

Leider sind die anti-human IgGs nicht die Kontrollen, die wir Ihnen als Isotypkontrolle für die IL9- und IL9R- Antikörper empfehlen würden. (Damit würden Sie sicher eine Färbung ...

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Thank you for contacting us. I have heard back from the lab with the following information: This antibody was only tested on human tissues and not on any other species. Therefore, we do not know if it would crossreact with mouse or not. I am sor...

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Thank you for contacting us and I'm sorry to hear that you're having some trouble staining with ab2410. We haven't tested this antibody using monkey tissue, only human tissue (tonsil), so we haven't optimized the protocol for monkey. However, I've ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"