Anti-Human Ig light chain抗体[MHK-49] (ab48536)


  • 产品名称Anti-Human Ig light chain抗体[MHK-49]
    参阅全部 Human Ig light chain 一抗
  • 描述
    小鼠单克隆抗体[MHK-49] to人Ig light chain
  • 特异性This antibody is specific for both soluble and membrane human immunoglobulin light chain kappa. It does not react with human immunoglobulin light chain lambda or heavy chain mu.
  • 经测试应用适用于: ICC/IF, ELISA, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein corresponding to Human Human Ig light chain.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号MHK-49
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域


Our Abpromise guarantee covers the use of ab48536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration. This antibody can be used as primary or secondary reagent for immunofluorescent staining or ELISA analysis.
Flow Cyt Use 0.5µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • 相关性There are only two types of light chain: kappa and lambda in mammals. Other types of light chains are found in lower vertebrates as the Ig-Light-Iota chain in Chondrichthyes and Teleostei. In each antibody, only one type is present and the two chains are identical. Each light chain has two successive domains: one constant and one variable domain. In humans 60% of light chains are kappa and 40% lambda,whereas in the mouse 95% of light chains are kappa. The amino acid sequences of lambda chains vary slightly at a few positions, allowing them to be classified into subtypes. The number of subtypes varies between species. Monoclonal immunoglobulin free light chains (FLC) are found in the serum and urine (Bence-Jones protein) of patients with a number of B-cell proliferative disorders, including multiple myeloma. Changes in serum FLC concentrations can provide a rapid and sensitive indication of response to treatment.
  • 细胞定位Cell Membrane: single-pass type I membrane protein and Secreted
  • 数据库链接
  • 别名
    • HCAK1 antibody
    • Ig kappa chain antibody
    • IGKC antibody
    • Immunoglobulin kappa constant antibody
    • immunoglobulin kappa light chain (VJ) antibody
    • kappa 1 immunoglobulin light chain antibody
    • KM antibody
    • MGC111575 antibody
    • MGC62011 antibody
    • MGC72072 antibody
    • MGC88770 antibody
    • MGC88771 antibody
    • MGC88809 antibody
    see all

Anti-Human Ig light chain antibody [MHK-49] (ab48536)参考文献

ab48536 has not yet been referenced specifically in any publications.

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