概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      GGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFK

技术指标

Our Abpromise guarantee covers the use of ab111673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • D2HGA2
    • ICD-M
    • IDH
    • IDH2
    • IDHM
    • IDHP_HUMAN
    • IDP
    • IDPM
    • Isocitrate dehydrogenase [NADP], mitochondrial
    • Isocitrate dehydrogenase 2 (NADP+), mitochondrial
    • mNADP-IDH
    • NADP(+)-specific ICDH
    • Oxalosuccinate decarboxylase
    see all
  • 功能
    Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex.
  • 疾病相关
    D-2-hydroxyglutaric aciduria 2
    Glioma
    enetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma.
  • 序列相似性
    Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  • 翻译后修饰
    Acetylation at Lys-413 dramatically reduces catalytic activity. Deacetylated by SIRT3.
  • 细胞定位
    Mitochondrion.
  • Information by UniProt

文献

ab111673 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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