概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      EVTGDAGVPESGEIRTLKPC Amino acids 2 to 21 of human DFF45/35 (1)
    • 氨基酸
      2 to 21

技术指标

Our Abpromise guarantee covers the use of ab8442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

    Western blot

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

常规信息

  • 别名
    • A330085O09Rik
    • Caspase activated deoxyribonuclease inhibitor short form
    • DFF 1
    • DFF 45
    • DFF alpha
    • DFF-45
    • DFF1
    • DFF35
    • DFF45
    • DFFA
    • Dffa DNA fragmentation factor, alpha subunit
    • DFFA_HUMAN
    • DNA fragmentation factor 45 kDa subunit
    • DNA Fragmentation Factor Alpha Subunit
    • DNA fragmentation factor subunit alpha
    • DNA fragmentation factor, 45 kD, alpha subunit
    • DNA fragmentation factor, 45kDa, alpha polypeptide
    • DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1
    • DNA fragmentation factor, alpha subunit
    • DNAation factor 45 kDa subunit
    • H13
    • ICAD
    • ICAD L
    • ICAD S
    • Inhibitor of CAD
    • Inhibitor of Caspase Activated DNase
    • MGC143066
    • OTTHUMP00000001903
    • OTTHUMP00000001904
    • RP23 121D17.3
    see all
  • 功能
    Inhibitor of the caspase-activated DNase (DFF40).
  • 序列相似性
    Contains 1 CIDE-N domain.
  • 翻译后修饰
    Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

文献

ab8442 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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