概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human
    • 序列
      C-TGPPAKKAISELP
    • 氨基酸
      135 to 147

相关产品

技术指标

Our Abpromise guarantee covers the use of ab23067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Iba1 antibody (ab5076)

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • AIF 1
    • AIF-1
    • Aif1
    • AIF1 protein
    • AIF1_HUMAN
    • Allograft inflammatory factor 1
    • Allograft inflammatory factor 1 splice variant G
    • allograft inflammatory factor-1 splice variant Hara-1
    • balloon angioplasty responsive transcription
    • BART 1
    • G1
    • G1 putative splice variant of allograft inflamatory factor 1
    • IBA 1
    • IBA1
    • interferon gamma responsive transcript
    • Interferon responsive transcript 1
    • interferon responsive transcript factor 1
    • Ionized calcium binding adapter molecule 1
    • ionized calcium-binding adapter molecule
    • Ionized calcium-binding adapter molecule 1
    • IRT 1
    • IRT1
    • Microglia response factor
    • MRF1
    • Protein g1
    see all
  • 功能
    Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
  • 组织特异性
    Detected in T-lymphocytes and peripheral blood mononuclear cells.
  • 序列相似性
    Contains 2 EF-hand domains.
  • 翻译后修饰
    Phosphorylated on serine residues.
  • 细胞定位
    Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
  • Information by UniProt

文献

ab23067 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for contacting us.

Unfortunately, we do not have a negative control image for ICC at hand.

However, we do have the peptide available, which can be used as as blocking peptide in this case to check if the astrocytes staining ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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