概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-DRHKETLKSKTQ
    • 氨基酸362 to 373

相关产品

技术指标

Our Abpromise guarantee covers the use of ab48064 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-HSD3B1 antibody (ab48018)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • 3 beta and steroid delta isomerase 1
    • 3 beta and steroid hydroxy delta 5 steroid dehydrogenase
    • 3 beta HSD I
    • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I
    • 3-beta-HSD I
    • 3-beta-hydroxy-5-ene steroid dehydrogenase
    • 3BETAHSD
    • 3BH
    • 3BHS1_HUMAN
    • 3BHSD
    • Delta-5-3-ketosteroid isomerase
    • HGNC:5217
    • HSD3B
    • HSD3B1
    • HSDB3
    • HSDB3A
    • Hydroxy delta 5 steroid dehydrogenase
    • Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1
    • Progesterone reductase
    • SDR11E1
    • Steroid Delta-isomerase
    • trophoblast antigen
    • Trophoblast antigen FDO161G
    see all
  • 功能3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.
  • 组织特异性Placenta and skin. Predominantly expressed in mammary gland tissue.
  • 通路Lipid metabolism; steroid biosynthesis.
  • 序列相似性Belongs to the 3-beta-HSD family.
  • 细胞定位Endoplasmic reticulum membrane. Mitochondrion membrane.
  • Information by UniProt

Human HSD3B1 peptide (ab48064)参考文献

ab48064 has not yet been referenced specifically in any publications.

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