概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab90993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • AI385591
    • AI874987
    • Homeo box 4D
    • Homeo box D10
    • Homeobox D10
    • Homeobox protein Hox-4D
    • Homeobox protein Hox-4E
    • Homeobox protein Hox-D10
    • Hox 4.4
    • Hox 4.5
    • Hox 4D
    • Hox 4E
    • Hox 5.3
    • HOX4D
    • HOX4E
    • HOXD10
    • HXD10
    • HXD10_HUMAN
    • OTTMUSP00000017845
    • RP23-313J15.9
    see all
  • 功能Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 组织特异性Strongly expressed in the adult male and female urogenital tracts.
  • 疾病相关Defects in HOXD10 are a cause of congenital vertical talus (CVT) [MIM:192950]; also known as rocker-bottom foot deformity or congenital convex pes valgus. CVT is a dislocation of the talonavicular joint, with rigid dorsal dislocation of the navicular over the neck of the talus. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity.
  • 序列相似性Belongs to the Abd-B homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 发展阶段Expressed in the developing limb buds.
  • 细胞定位Nucleus.
  • Information by UniProt

Human HOXD10 peptide (ab90993)参考文献

ab90993 has not yet been referenced specifically in any publications.

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