概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab71589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 纯度70 - 90% by HPLC.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Adenosine 5' monophosphoramidase
    • Adenosine 5''-monophosphoramidase
    • HINT 1
    • HINT1
    • HINT1_HUMAN
    • Histidine triad nucleotide binding protein 1
    • Histidine triad nucleotide-binding protein 1
    • PKCI 1
    • PKCI-1
    • PKCI1
    • PRKCNH1
    • Protein kinase C inhibitor 1
    • Protein kinase C interacting protein 1
    • Protein kinase C-interacting protein 1
    see all
  • 功能Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the HINT family.
    Contains 1 HIT domain.
  • 结构域The histidine triad, also called HIT motif, forms part of the binding loop for the alpha-phosphate of purine mononucleotide.
  • 细胞定位Cytoplasm. Nucleus. Interaction with CDK7 leads to a more nuclear localization.
  • Information by UniProt

Human HINT1 peptide (ab71589)参考文献

ab71589 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"