概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-HFGLFPANYVKLLE
    • 氨基酸473 to 486

技术指标

Our Abpromise guarantee covers the use of ab22787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • Cortactin like
    • CTTNL
    • HCLS 1
    • Hcls1
    • HCLS1_HUMAN
    • Hematopoietic cell specific Lyn substrate 1
    • Hematopoietic cell-specific LYN substrate 1
    • Hematopoietic lineage cell-specific protein
    • HS 1
    • HS1
    • LckBP1
    • OTTHUMP00000215180
    • OTTHUMP00000215182
    • p75
    see all
  • 功能Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
  • 组织特异性Expressed only in tissues and cells of hematopoietic origin.
  • 序列相似性Contains 4 cortactin repeats.
    Contains 1 SH3 domain.
  • 发展阶段Expressed in early stage of myeloid and erythroid differentiation.
  • 翻译后修饰Phosphorylated by LYN; rapidly after cross-linking of surface IgM on B-cells.
  • 细胞定位Membrane. Cytoplasm. Mitochondrion.
  • Information by UniProt

Human HCLS1 peptide (ab22787)参考文献

ab22787 has not yet been referenced specifically in any publications.

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