人Growth Hormone ELISA试剂盒(ab108643)

概述

  • 产品名称
    人Growth Hormone ELISA试剂盒
    参阅全部 Human Growth Hormone 试剂盒
  • 检测方法
    Colorimetric
  • 样品类型
    Serum
  • 检测类型
    Sandwich (quantitative)
  • 灵敏度
    = 0.5 ng/ml
  • 范围
    0.5 ng/ml - 50 ng/ml
  • 实验步骤
    Multiple steps standard assay
  • 种属反应性
    与反应: Human
  • 产品概述

    ab108643 Human Growth Hormone Human ELISA Kit is intended for the quantitative determination of the Human Growth Hormone (HGH) concentration in human serum.


    Human Growth Hormone (HGH, somatotropin) is a polypeptide secreted by the anterior pituitary. It is 191 amino acids in length and has a molecular mass of approximately 22,000 daltons. Its metabolic effects are primarily anabolic. Human Growth Hormone promotes protein conservation and is engaged in a wide range of mechanisms for protein synthesis. It also enhances glucose transport and facilitates glycogen storage. Its cascade of growth-promoting action is mediated by another family of peptide hormones, the somatomedins. Human Growth Hormone measurement is primarily of interest in the diagnosis and treatment of various forms of abnormal growth hormone secretion. Disorders caused by hyposecretion include dwarfism and unattained growth potential, and hypersecretion is associated with gigantism and acromegaly.


    Get results in 90 minutes with Human Growth Hormone ELISA Kit (ab190811) from our SimpleStep ELISA® range.


     


     

  • 经测试应用
    适用于: ELISAmore details
  • 平台
    Microplate

性能

  • 存放说明
    Store at +4°C. Please refer to protocols.
  • 组件 1 x 96 tests
    Enzyme Conjugate Reagent 1 x 13ml
    HGH Standard 5 ng/ml 1 x 1ml
    HGH Standard 0 ng/ml 1 x 1ml
    HGH Standard 10 ng/ml 1 x 1ml
    HGH Standard 2.5 ng/ml 1 x 1ml
    HGH Standard 25 ng/ml 1 x 1ml
    HGH Standard 50 ng/ml 1 x 1ml
    Sheep Anti-Human Growth Hormone-Coated microtiter plate 1 x 96 tests
    Stop Solution 1 x 12ml
    TMB Substrate Solution 1 x 11ml
  • 研究领域
  • 功能
    Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
  • 疾病相关
    Defects in GH1 are a cause of growth hormone deficiency isolated type 1A (IGHD1A) [MIM:262400]; also known as pituitary dwarfism I. IGHD1A is an autosomal recessive deficiency of GH which causes short stature. IGHD1A patients have an absence of GH with severe dwarfism and often develop anti-GH antibodies when given exogenous GH.
    Defects in GH1 are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH. Dwarfism is less severe than in IGHD1A and patients usually respond well to exogenous GH.
    Defects in GH1 are the cause of Kowarski syndrome (KWKS) [MIM:262650]; also known as pituitary dwarfism VI.
    Defects in GH1 are a cause of growth hormone deficiency isolated type 2 (IGHD2) [MIM:173100]. IGHD2 is an autosomal dominant deficiency of GH which causes short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy.
  • 序列相似性
    Belongs to the somatotropin/prolactin family.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 别名
    • gH
    • GH-N
    • GH1
    • GHN
    • Growth hormone
    • Growth hormone 1
    • HGH
    • Pituitary growth hormone
    • SOMA_HUMAN
    • Somatotropin
    see all
  • 数据库链接

相关产品

应用

Our Abpromise guarantee covers the use of ab108643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

图片

  • Human Growth Hormone Standard curve

实验方案

文献

ab108643 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your message and inquiry. The HGH ELISA has been validated using serum without additives. We have not tested the kit using additives and cannot guarantee that it would be compatible with the assay.

SPECIMEN COLLECTION AND PREPARA...

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Thank you for your reply.

The liquid matrix is serum and the conversion factor for HGH is 1 ng is about 2.2 uIU.

I hope this information helps. Please contact us with any other questions.

Thank you for your inquiry and your patience with this reply as I was awaiting more information from the lab.

The kit was recently changed to include the standards in liquid form. We are currently updating the product insert, which will be a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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