人Glucose Transporter GLUT2肽(ab105630)

概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Human

相关产品

技术指标

Our Abpromise guarantee covers the use of ab105630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Glucose Transporter GLUT2 antibody (ab95256)

  • 纯度
    70 - 90% by HPLC.

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Glucose Transporter 2
    • Glucose Transporter GLUT2
    • Glucose transporter type 2
    • Glucose transporter type 2 liver
    • Glucose transporter, liver/islet
    • GLUT-2
    • GLUT2
    • GTR2_HUMAN
    • GTT2
    • liver
    • SLC2A2
    • Solute carrier family 2 (facilitated glucose transporter) member 2
    • Solute carrier family 2 facilitated glucose transporter member 2
    • Solute carrier family 2, facilitated glucose transporter member 2
    see all
  • 功能
    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
  • 组织特异性
    Liver, insulin-producing beta cell, small intestine and kidney.
  • 疾病相关
    Fanconi-Bickel syndrome
  • 序列相似性
    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • 翻译后修饰
    N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
  • 细胞定位
    Membrane.
  • Information by UniProt

文献

ab105630 has not yet been referenced specifically in any publications.

客户评价及客户问答

Abreviews
Application
Western blot
We have used whole kidney lysate form normoglycemic mice or STZ induced diabetic mice after 16 weeks from injection.

Application: Western blot
Sample: whole Kidney lysate
Gel Running Conditions: Reduced Denaturing
Loading amount: 30 µg

Treatment: Five consecutive intraperitoneal Strreptozotocin injections (Cayman Chemical 50 mg/kg per day), Samples from kidneys after 16 weeks from last injection.
Specification: Mouse Kidney
Blocking step: Milk as blocking agent for 1 hour, Temperature: 25°C

First antibody (ab95256) with/ without Blocking peptide (ab105630), ratio 1:10-
Incubation time 16 hour(s) , Temperature: 4°C
Dilution 1/1000

Secondary antibody
Dilution 1/10000
Name ab97085
Host species: Rabbit
Clonality: Polyclonal
Conjugation: Horse Radish Peroxidase
Detection
Detection method ECL+
Exposure 2 minute(s) and 0 second(s)


lanes 1-3, 7-9 are from WT normoglycemic mice
lanes 4-6, 10-12 are from STZ induced diabetic mice

lanes 1-6 with ab95256
lanes 7-12 with ab95256+ ab105630

STZ- Streptozotocine
bp- Blocking peptide
Username

Shiran Udi

Verified customer

提交于 Jul 03 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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