人Glucose Transporter GLUT1肽(ab115830)

概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 氨基酸478 to 492

相关产品

技术指标

Our Abpromise guarantee covers the use of ab115830 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Glucose Transporter GLUT1 antibody (ab652)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Constituent: dH2O

常规信息

  • 别名
    • Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity)
    • CSE
    • DYT17
    • DYT18
    • DYT9
    • EIG12
    • erythrocyte/brain
    • Erythrocyte/hepatoma glucose transporter
    • facilitated glucose transporter member 1
    • Glucose transporter 1
    • Glucose transporter type 1
    • Glucose transporter type 1, erythrocyte/brain
    • GLUT
    • GLUT-1
    • GLUT1
    • GLUT1DS
    • GLUTB
    • GT1
    • GTG1
    • Gtg3
    • GTR1_HUMAN
    • HepG2 glucose transporter
    • HTLVR
    • Human T cell leukemia virus (I and II) receptor
    • MGC141895
    • MGC141896
    • PED
    • RATGTG1
    • Receptor for HTLV 1 and HTLV 2
    • SLC2A1
    • Solute carrier family 2
    • Solute carrier family 2 (facilitated glucose transporter), member 1
    • Solute carrier family 2, facilitated glucose transporter member 1
    see all
  • 功能Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
  • 组织特异性Expressed at variable levels in many human tissues.
  • 疾病相关Defects in SLC2A1 are the cause of glucose transporter type 1 deficiency syndrome (GLUT1DS) [MIM:606777]; also known as blood-brain barrier glucose transport defect. This disease causes a defect in glucose transport across the blood-brain barrier. It is characterized by infantile seizures, delayed development, and acquired microcephaly.
    Defects in SLC2A1 are the cause of dystonia type 18 (DYT18) [MIM:612126]. DYT18 is an exercise-induced paroxysmal dystonia/dyskinesia. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYT18 is characterized by attacks of involuntary movements triggered by certain stimuli such as sudden movement or prolonged exercise. In some patients involuntary exertion-induced dystonic, choreoathetotic, and ballistic movements may be associated with macrocytic hemolytic anemia.
  • 序列相似性Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cell membrane. Melanosome. Localizes primarily at the cell surface (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Human Glucose Transporter GLUT1 peptide (ab115830)参考文献

ab115830 has not yet been referenced specifically in any publications.

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Thank you for contacting us. I can finally confirm that the peptide products are now available on our website. Peptide for ab652 = ab115830 Peptide for ab654 = ab115831 I hope this information is helpful to you. Please do not ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"