概述

  • 产品名称人FOXH1肽

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列GPCSGSRLGPPEAE
    • 氨基酸2 to 15

技术指标

Our Abpromise guarantee covers the use of ab23092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • FAST 1
    • Fast 2
    • Fast-1
    • Fast-2
    • FAST1
    • Fast2
    • Forkhead activin signal transducer 1
    • Forkhead activin signal transducer 2
    • Forkhead box H1
    • Forkhead box protein H1
    • FOX H1
    • FOXH 1
    • FOXH1
    • FOXH1_HUMAN
    • hFAST 1
    • hFAST-1
    • hFAST1
    • Human homolog of Xenopus forkhead activin signal transducer 1
    • TGF beta/Activin signal transducer FAST1
    see all
  • 功能Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
  • 组织特异性Ubiquitous.
  • 序列相似性Contains 1 fork-head DNA-binding domain.
  • 结构域The FM region is required for binding SMAD2/SMAD4 complexes. FM2 is more effective than FM1 and only interacts with phosphorylated SMAD2 that is in an activated SMAD complex.
  • 细胞定位Nucleus.
  • Information by UniProt

Human FOXH1 peptide (ab23092)参考文献

ab23092 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23092.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"