概述

描述

  • 性质Synthetic
  • 氨基酸序列

技术指标

Our Abpromise guarantee covers the use of ab19644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-FOXG1 antibody - ChIP Grade (ab18259), Anti-FOXG1 antibody [mAbcam 51774] (ab51774)

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • BF-1
    • BF-2
    • BF1
    • BF2
    • Brain factor 1
    • Brain factor 2
    • FHKL
    • FKH2
    • FKHL1
    • FKHL2
    • FKHL3
    • FKHL4
    • Forkhead box protein G1
    • Forkhead box protein G1A
    • Forkhead box protein G1B
    • Forkhead box protein G1C
    • Forkhead like 1
    • Forkhead like 2
    • Forkhead like 3
    • Forkhead like 4
    • Forkhead-related protein FKHL1
    • Forkhead-related protein FKHL2
    • Forkhead-related protein FKHL3
    • FOXG1
    • FOXG1_HUMAN
    • FOXG1A
    • FOXG1B
    • FOXG1C
    • HBF 1
    • HBF G2
    • hBF-2
    • HBF2
    • HFK1
    • HFK2
    • HFK3
    • KHL2
    • Oncogene QIN
    • QIN
    see all
  • 功能Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
  • 组织特异性Expression is restricted to the neurons of the developing telencephalon.
  • 疾病相关Defects in FOXG1 are the cause of congenital variant of Rett syndrome (RTTCV) [MIM:613454]. RTTCV is a severe neurodevelopmental disorder with features of classic Rett syndrome but earlier onset in the first months of life. Clinical features include progressive microcephaly, hypotonia, irresponsiveness and irritability in the neonatal period, mental retardation, psychomotor regression and stereotypical movements.
  • 序列相似性Contains 1 fork-head DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Human FOXG1 peptide (ab19644)参考文献

ab19644 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"